New-generation columns are Cytiva’s IEX columns deliver the highest resolution, for laboratory-scale purification. Capto HiRes Q and Capto HiRes S are prepacked columns for high-resolution purification of proteins, peptides, polynucleotides, and other biomolecules by ion exchange chromatography. The prepacked columns effectively separate biomolecules with small differences in net surface charge and are therefore well suited to preparation of highly pure proteins in, for example, structural studies and protein analysis.

• Capto HiRes Q - Strong anion exchanger (quaternary ammonium) -CH2-N+ (CH3)3
• Capto HiRes S - Strong cation exchanger (methyl sulfonate) -CH2-SO3-
• Suitable for preparing highly pure proteins—essential in techniques such as structural studies using cryo-electron microscopy or protein crystallography
• Suitable for protein analysis in research or quality control—for example, for characterisation of target protein charge variants
• High quality column—excellent reproducibility, durability, and high chemical and pH stabilities
• Replacement for Mono Q™ and Mono S™ columns—delivering similar or improved resolution and similar protein elution for an easy transition from one column protocol to the other