1.1.1-Trichloro-2-Methyl-2-Propanol Hemihydrate

Code: 20801-25kg D2-231

Not available outside of the UK & Ireland.

Application

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) is a preservative used as a standard for quantifying preservatives in pharmaceutical formulations ...


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$2,233.00 25KG
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Not available outside of the UK & Ireland.

Application

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) is a preservative used as a standard for quantifying preservatives in pharmaceutical formulations by using capillary electrophoretic method. It has also been used to anesthetize leeches for preparing c-DNA library from regenerating retzius cells.

Biochem/physiol Actions

Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.

anion traceschloride (Cl-): ≤100 mg/kg
application(s)pharmaceutical (small molecule)
assay98-100.5% (calc with ref. to anhyd. subst.)
formsolid
ign. residue≤0.1% (as SO4)
impurities≤0.002% heavy metals (as Pb), 4.5-5.5% water (Karl Fischer)
InChI keyWRWLCXJYIMRJIN-UHFFFAOYSA-N
InChI1S/2C4H7Cl3O.H2O/c2*1-3(2,8)4(5,6)7;/h2*8H,1-2H3;1H2
mp76-80 °C
Quality Level200
qualitymeets analytical specification of Ph. Eur., BP, NF
SMILES stringO.CC(C)(O)C(Cl)(Cl)Cl.CC(C)(O)C(Cl)(Cl)Cl
Cas Number6001-64-5
This product has met the following criteria to qualify for the following awards:



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