Not available outside of the UK & Ireland.

Application

This enzyme is useful for enzymatic determination of inorganic phosphorus, 5′-nucleotidase and adenosine deaminase when coupled with Purine-nucleoside phosphorylase (PNP-301) and uricase (UAO-201, UAO-211).

Biochem/physiol Actions

Also contains proteolytic activity.

General description

Allopurinol is a synthetic drug show to inhibit xanthine oxidase.

Packaging

25, 100 units in glass bottle

Physical form

Lyophilized powder containing BSA and sodium glutamate as stabilizers

Physical properties

Inhibitors: Reducing agents, Hg⁺⁺, Ag⁺,MIAOptimum pH: 7.5 - 8.0 Optimum temperature: 65^oCpH Stability: pH 6.5 - 9.0 (25^oC, 15hr) Thermal stability: below 55^oC (pH 8.0, 30min)

Unit Definition

One unit will convert 1.0 µmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.