Not available outside of the UK & Ireland.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biochem/physiol Actions

The tumor suppressor gene P53 was shown to be a target of ubiquitin-specific protease 5.

General description

Human USP5 (Ubiquitin-Specific Protease 5) or Isopeptidase T (isoT), amino acids 2-858 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system.

Physical form

Solution in 40 mM Tris-HCl, 110 mM NaCl, 2.2 mM KCl, 80 ng/µl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0.