Not available outside of the UK & Ireland.

Application

10 mM calcium chloride is used for activation of the enzyme.

Transglutaminase has been used in a study to improve quantifiable assays to fully characterize the role of transglutaminase in diseases such as Huntington′s disease and Alzheimer′s disease.Transglutaminase has also been used in a study to develop a nonradioactive dot blot assay for transglutaminase activity.

Physical form

Lyophilized from 50 mM NaH₂PO₄, 150 mM NaCl, pH 8. Contains maltodextrin.

Unit Definition

One unit will catalyze the formation of 1.0 µmole of hydroxamate per minute from Nα-Z-Gln-Gly and hydroxylamine at pH 6.0 at 37 °C. (L-Glutamic acid γ-monohydroxamate is the standard.)