Not available outside of the UK & Ireland.

Application

Superoxide dismutase-polyethylene glycol from bovine erythrocytes has been used:in the incubation of lung slices for measurement of dihydroethidium (DHE) fluorescence in cultured bovine pulmonary artery endothelial cellsas supplement in T cell culture to investigate its effect on cytokine productionin the preincubation of the carotid artery sections prior to DHE treatment

Biochem/physiol Actions

Superoxide dismutase-polyethylene glycol (SOD-PEG) is effective than SOD in scavenging free radicals in injuries. It reduces oxidative damage in ovarian follicles cell culture and during ovarian tissue transplantation. SOD-PEG is also effective in scavenging superoxide in mitochondrial abnormalities.

General description

Superoxide dismutase from bovine erythrocytes is a copper and zinc superoxide dismutase. Copper and zinc ions are coordinated by active site histidine residues. It has β-barrel structure.

Other Notes

Superoxide dismutase from bovine erythrocytes coupled to methoxy-polyethylene glycol, M.W. 5,000, through secondary amine linkage.

Packaging

Package size based on protein content

Physical form

Lyophilized powder containing PEG plus 5% citrate buffer salts

Preparation Note

Enzyme derived