Not available outside of the UK & Ireland.

Application

Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. It has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis.

Biochem/physiol Actions

Calcium is required for peptidylarginine deiminase activity in vitro.

General description

Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline.

Packaging

25 units in poly bottle

Physical form

Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol

Unit Definition

One unit will produce 1 µmole of N-α-benzoylcitrulline ethyl ester from BAEE per hr at 55 °C at pH 7.2.