Not available outside of the UK & Ireland.

Biochem/physiol Actions

β-Lactamases exhibit high carbapenemase activity. β-lactamases can destroy the β-lactam ring. Truecarbapenemaseshas the ability to hydrolyseseveral β-lactam ring containing carbapenems like meropenem, doripenem, imipenem and ertapenem.

Components

600-1500 IU beta-lactamase I per vial60-150 IU beta-lactamase II per vial

General description

No detectable growth in tryptone soy broth at 30-35 °C for 14 days

Physical form

Lyophilized powder containing sodium chloride, potassium phosphate, dipotassium phosphate and sorbitol.

Unit Definition

One unit will hydrolyze 1.0 µmole substrate per min (βI: benzylpenicillin; βII: cephalosporin C) in phosphate buffer, pH 7.0 at 25°C.