Cytochrome P450 2C9*2 (R144C), human, recombinant, expressed in E. coli

Code: h4667-1000pmo D2-231

Not available outside of the UK & Ireland.

General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Other Notes

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Not available outside of the UK & Ireland.

General description

Supplied as purified soluble proteins, rather than microsomal preparations.

Other Notes

Visit our drug metabolism resources: www.sigmaaldrich.com/life-science/metabolomics/enzyme-explorer/cell-signaling-enzymes/xenobiotics.html

Unit Definition

One unit will convert 1.0 nanomole of diclofenac (2-(2,6-dichloranilino) phenylacetic acid) 4`-hydroxylated product per minute at pH 7.4 at 37 °C.

biological sourcehuman
concentration50-150 nmol/mL (P450), 6-14 ng/mg protein (specific content), 3.5-25 mg protein/mL (protein)
descriptionpurified, soluble
formliquid
Gene Informationhuman ... CYP2C9(1559)
mol wt54370 g/mol
NCBI accession no.NP_000762.2
Quality Level200
recombinantexpressed in E. coli
shipped indry ice
specific activity12-88 units/mg protein
storage temp.−70°C
This product has met the following criteria: