Not available outside of the UK & Ireland.

Application

L-Glutamate Oxidase from Streptomyces sp has been used to determine the enzyme activity of the immobilized glutamate oxidase (GOx). It has also been used as a component of imaging buffer for stochastic optical reconstruction microscopy (STORM) imaging.

Biochem/physiol Actions

Major enzyme in the synthesis or degradation of glutamic acid; transfers an amine to α-ketoglutaric acid to form L-glutamic acid or deamidates L-glutamic acid

L-glutamate oxidase catalyzes the conversion of L-glutamate to 2-oxoglutarate.

General description

Glutamate is a non-essential amino acid. It acts as a primary excitatory neurotransmitter. In major trauma, major surgery, sepsis and bone marrow transplantation, glutamate functions as an essential amino acid.

Unit Definition

One unit will form 1.0 µmole of α-ketoglutaric acid from L-glutamic acid per min at pH 7.4 at 30 °C.