Not available outside of the UK & Ireland.

Application

Creatine kinase MM fraction from human heart has been used in a study to investigate the importance of intraoperative and postoperative cardiac medical therapy in emergency coronary artery bypass grafting for acute myocardial infarction. Creatine kinase MM fraction from human heart has also been used in a study to investigate the circadian dependence of infarct size and left ventricular function after ST slevation myocardial infarction.

Biochem/physiol Actions

May be used as a control or calibrator in monitoring myocardial injury.

Physical form

Lyophilized powder containing Tris-HCl, EDTA and N-acetyl cysteine.

Specificity

One unit will transfer 1.0 µmole of phosphate from creatine phosphate to ADP per minute at 37 °C (measured at 340 nm as one equimolar amount of NADH produced by coupled reaction).

Unit Definition

One unit will transfer one micromole of phosphate from creatine phosphate to ADP per minute at 37 deg C.

Warning

All human source materials have tested negative for HIV1, HIV2, HCV antibodies and HbsAg. No test guarantees a product to be non-infectious. Therefore, all material derived from human fluids or tissues should be considered as potentially infectious.