Not available outside of the UK & Ireland.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Biochem/physiol Actions

Ubiquitin-specific protease 10 (USP10) expression has been shown to be induced by vasopressin. In HEK293 cells, USP10 was shown to deubiquitylate sorting nexin 3.

General description

Human USP10 (Ubiquitin-Specific Protease 10) or Ubiquitin C-terminal Hydrolase 10, amino acids 2-798 (end) with an N-terminal FLAG-tag, expressed in a baculovirus-infected Sf9 cell expression system.

Physical form

Solution in 40 mM Tris-HCl, 110 mM NaCl, 2.2 mM KCl, 80 ng/µl Flag peptide, 3 mM DTT, and 20% Glycerol at pH 8.0.