Not available outside of the UK & Ireland.

Application

Kallikrein from porcine pancreas has been used: as a matrix metalloproteinase-9 (MMP-9) zymogen activatoras a component of cell culture to test its effect on rat subventricular zone (SVZ) cells and oligodendrocyte progenitor cells (OPC) proliferation and survivalas a model enzyme to track kinetic data and visual detection limits of hydrolysis by hydrolytic enzymes in the two-phases array

Biochem/physiol Actions

Kallikrein active forms are generated by the enzymatic action of trypsin. It is a serine protease that mediates the activation of growth factors and substrates.

General description

Kallikrein exists as an inactive prokallikrein in the porcine pancreas. The porcine kallikrein gene region is localized on chromosome 6q12-q21.

Packaging

250, 1000 units in poly bottle

Unit Definition

One unit will hydrolyze 1.0 µmole of Nα-benzoyl-L-arginine ethyl ester (BAEE) to Nα-benzoyl-L-arginine and ethanol per min at pH 8.7 at 25°C.