L-Glutamic Dehydrogenase from bovine liver, Type I, ammonium sulfate suspension, >=40 units/mg protein

Code: g2501-50mg D2-231

Not available outside of the UK & Ireland.

Analysis Note

Protein determined by biuret

Biochem/physiol Actions

L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutar...


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Your Price
$311.75 50MG

Not available outside of the UK & Ireland.

Analysis Note

Protein determined by biuret

Biochem/physiol Actions

L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutarate.

Mammalian forms of this enzyme, including this bovine form, can use either NADP(H) or NAD(H) as coenzymes. L-glutamic dehydrogenase plays a unique role in mammalian metabolism. The reverse reaction catalyzed by this enzyme is the only pathway by which ammonia can become bound to the α-carbon atom of an α-carboxylic acid and thus, is the only source of de novo amino acid synthesis in mammalian species. The bovine enzyme is characterized by three sets of properties: It has a reversible concentration-dependent association, producing higher molecular weight forms. Forms tight enzyme-reduced coenzyme-substrate ternary complexes whose rates of dissociation modulate the steady-state reaction rates. Exhibits a wide variety of effects from the binding of any of a number of nucleotide modifiers.L-glutamic dehydrogenase catalyzes the conversion of glutamate to α-ketoglutarate.

Packaging

50 mg in glass bottle

Physical form

Suspension in 2.0 M (NH4)2SO4 solution

Unit Definition

One unit will reduce 1.0 µmole of α-ketoglutarate to L-glutamate per min at pH 7.3 at 25 °C, in the presence of ammonium ions.

formammonium sulfate suspension
Gene Informationcow ... GLUD1(281785)
mol wt310-350 kDa
Quality Level200
specific activity≥40 units/mg protein
storage temp.2-8°C
typeType I
UniProt accession no.P00366
Code
Description
Unit Size
List Price
Qty
Cas Number9029-12-3
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