Not available outside of the UK & Ireland.

Application

DL-β-Hydroxybutyric acid sodium salt has been used:as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cowsto investigate its anticonvulsant effects in epilepsy induced ratsto induce hyperketonemia in Holstein dairy cows

Biochem/physiol Actions

β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD⁺, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).

Packaging

5, 25, 100 g in poly bottle