Not available outside of the UK & Ireland.

Application

Rotenone has been used:to study its effect on cell proliferationto detect the production of cellular reactive oxygen species in isolated rat forebrain mitochondria to measure mitochondrial enzymatic activity

Biochem/physiol Actions

Rotenone is an inhibitor of mitochondrial electron transport at nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. It is readily absorbed through the exoskeletons of arthropods, but poorly absorbed cutaneously or from the gastrointestinal tract of mammals. Rotenone acts as a neurotoxic agent which can produce Parkinson-like condition to serve as an animal model for the study of etiology and interventions.

General description

Rotenone belongs to the retinoid family. It is naturally present in Leguminosa plants and is considered to be cytotoxic. It is commonly used as an insecticide and a pesticide.

Packaging

1, 5, 10, 25 g in glass bottle