Leflunomide, Immunosuppressant

Code: l5025-100mg D2-231

Not available outside of the UK & Ireland.

Application

By virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases...


read more

Your Price
$391.50 100MG
REQUEST

Not available outside of the UK & Ireland.

Application

By virtue of its immunosuppressant effects, leflunomide has found use in organ transplantation and treatment of rheumatoid arthritis and other autoimmune diseases.

Biochem/physiol Actions

Immunosuppressive; inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is believed to inhibit dihydroorotate dehydrogenase (in the de novo pyrimidine synthesis pathway) as well as several protein tyrosine kinases.

Packaging

25, 100 mg in poly bottle

assay≥98% (TLC)
formpowder
Gene Informationhuman ... DHODH(1723)
InChI keyVHOGYURTWQBHIL-UHFFFAOYSA-N
InChI1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
mode of actionenzyme | inhibits
mp166.5 °C
Quality Level200
SMILES stringCc1oncc1C(=O)Nc2ccc(cc2)C(F)(F)F
solubilitymethanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
L5025-25MG
Leflunomide, Immunosuppressant

Unit:25MG
List Price: $117.89
Source:List Price
ADD
Cas Number75706-12-6
Hazard Class6.1
Un Number2811
Pack Group3
This product has met the following criteria: