Filipin III from Streptomyces filipinensis, >=85% (HPLC)

Code: f4767-5mg D2-231

Not available outside of the UK & Ireland.

Application

Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membrane...


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Your Price
£837.00 5MG
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Not available outside of the UK & Ireland.

Application

Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membranes. It is also widely used to localize and quantitate unesterified cholesterol by virtue of a specific fluorescent complex.

Biochem/physiol Actions

Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action may be due to altering membrane permeability and associated functions by binding to membrane sterols. Filipin inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.

Other Notes

Filipin III is the major component of 8 isomeric components in filipin.

Packaging

1, 5 mg in glass bottle

antibiotic activity spectrumfungi, yeast
assay≥85% (HPLC)
formpowder
InChI keyIMQSIXYSKPIGPD-BWJOQPJXSA-N
InChI1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14-
mode of actioncell membrane | interferes
mp163-180 °C
Quality Level300
SMILES stringCCCCCC(O)C1C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)C(C)=CC=CC=CC=CC=CC(O)C(C)OC1=O
solubilitymethanol: 9.80-10.20 mg/mL, clear, colorless to yellow
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
F4767-1MG
Filipin III from Streptomyces filipinensis, >=85% (HPLC)

Unit:1MG
List Price: £167.00
Source:List Price
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Cas Number480-49-9
This product has met the following criteria: