Not available outside of the UK & Ireland.

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

L-Buthionine-sulfoximine has been used:as a selective activator for the induction of ferroptosis in rat apoptotic cellsas an inhibitor of γ-glutamylcysteine synthetase to study its effects on the viability and effectiveness of microspore embryogenesis (ME) induction in triticale and barleyas a glutathione synthesis blocker to study its effects on auranofin (AFN)-mediated interleukin-1β expression in murine alveolar macrophages

Biochem/physiol Actions

Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

Packaging

1, 5 g in poly bottle

500 mg in poly bottle