Not available outside of the UK & Ireland.
Application
Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.
L-Buthionine-sulfoximine has been used:as a selective activator for the induction of ferroptosis in rat apoptotic cellsas an inhibitor of γ-glutamylcysteine synthetase to study its effects on the viability and effectiveness of microspore embryogenesis (ME) induction in triticale and barleyas a glutathione synthesis blocker to study its effects on auranofin (AFN)-mediated interleukin-1β expression in murine alveolar macrophages
Biochem/physiol Actions
Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.
Packaging
1, 5 g in poly bottle
500 mg in poly bottle
This product has met the following criteria: