L-Buthionine-sulfoximine, >=97% (TLC)

Code: b2515-5g D2-231

Not available outside of the UK & Ireland.

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

L-Buthionine-sulfoximine has been used:as a s...


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Your Price
$1,103.45 5G
$1,324.14 inc. VAT

Not available outside of the UK & Ireland.

Application

Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

L-Buthionine-sulfoximine has been used:as a selective activator for the induction of ferroptosis in rat apoptotic cellsas an inhibitor of γ-glutamylcysteine synthetase to study its effects on the viability and effectiveness of microspore embryogenesis (ME) induction in triticale and barleyas a glutathione synthesis blocker to study its effects on auranofin (AFN)-mediated interleukin-1β expression in murine alveolar macrophages

Biochem/physiol Actions

Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. Used to induce experimental glutathione deficiency, to investigate roles of glutathione in cellular processes.

Packaging

1, 5 g in poly bottle

500 mg in poly bottle

assay≥97% (TLC)
biological sourcesynthetic (organic)
formpowder
Gene Informationhuman ... GCLC(2729), GCLM(2730)
InChI keyKJQFBVYMGADDTQ-CVSPRKDYSA-N
InChI1S/C8H18N2O3S/c1-2-3-5-14(10,13)6-4-7(9)8(11)12/h7,10H,2-6,9H2,1H3,(H,11,12)/t7-,14?/m0/s1
mp224-226 °C
Quality Level200
shipped inwet ice
SMILES stringCCCCS(=N)(=O)CC[C@H](N)C(O)=O
solubilitywater: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
B2515-1G
Unit:1G
List Price: $343.65
Source:List Price
ADD
B2515-500MG
Unit:500MG
List Price: $187.05
Source:List Price
ADD
Cas Number83730-53-4
This product has met the following criteria: