Irradiated PBMCs cannot proliferate but are alive and retain their cellular processes, including antigen processing and presentation and production of cytokines and other soluble factors. Irradiated PBMCs can be used as stimulator cells for rapid PBMC culture expansion, as antigen-presenting cells to present antigen to T cells, as feeder cells to support the culture of target cells (e.g., CAR-T cells), or as stimulator cells in mixed lymphocyte reactions.
This product has met the following criteria: