The Corning® Elplasia® 12K flask enables researchers to generate a high density of spheroids in a scaffold-free model. The Elplasia® 12K Flask contains 152 microcavities per cm², in a vessel footprint similar to that of a T-75 flask. Gravity, in conjunction with the Corning® Ultra-Low Attachment (ULA) surface, and a rounded microcavity geometry enable formation of approximately 12,000 spheroids of similar shape and size. The ULA surface, a proprietary, animal-free, covalently bonded hydrogel, promotes the formation and easy harvesting of spheroids.

• Corning ULA surface
• Optically clear, gas permeable polystyrene film with low autofluorescence
• Liquid diverter feature to minimise impact of liquid flow during medium exchange steps and flask handling
• 80cm² surface area with 152 microcavities per cm² generate approximately 12,000 spheroids of uniform size and shape per flask
• Round well-bottom geometry
• Microcavity geometry dimensions: 850 x 650µm (top diameter x depth), with working spheroid growth dimensions of 500 x 600µm (diameter x depth)
• 25 to 50mL working volume