Not available outside of the UK & Ireland.

Amino Acid Sequence

Gly-Gly-His

Application

Gly-Gly-His has been used: as a peptide test probe in the hydrophilic interaction liquid chromatography (HILIC) studies in the electrochemical modification of back-side contact transducers (BSC) electrodes in copper (Cu²⁺) sensing studiesfor the fabrication carbon nanotube electrode for detection of Cu²⁺ ions

Biochem/physiol Actions

Gly-Gly-His (GGH) tripeptide displays the affinity of copper (Cu²⁺) complexation. These complexes display good skin tolerance and may be useful in wound healing. GGH copper complexes are proposed to reduce tumor necrosis factor α (TNF-α)-based interleukin 6 (IL-6) secretion by in vivo studies with fibroblasts. GGH is used in comparative studies with other imidazole-containing peptides such as carnosine. An area of active application research involves the GGH binding of copper ions.

General description

Gly-Gly-His (GGH) tripeptide with carboxyl-terminal histidine residue is hydrophilic.