Ofloxacin, fluoroquinolone antibiotic

Code: o8757-10g D2-231

Not available outside of the UK & Ireland.

Application

Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. It is given to patients before undergoing reti...


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Your Price
$217.50 10G

Not available outside of the UK & Ireland.

Application

Ofloxacin is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. It is a nalidixic acid analog. It is given to patients before undergoing retinal reattachment surgery.

Biochem/physiol Actions

Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, which haults DNA replication and cell division. Ofloxacin has been shown to convert LytA from the inactive E-form to the active C-form. It is a chiral molecule that inhibits pneumococcal cell wall-degrading virulence factors.

General description

Chemical structure: fluoroquinolone

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Packaging

1, 10 g in poly bottle

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria, mycobacteria
assay≥99% (HPLC)
biological sourcesynthetic
formpowder
Gene Informationhuman ... CSNK2A1(1457), KCNH1(3756)rat ... Gabra1(29705)
InChI keyGSDSWSVVBLHKDQ-UHFFFAOYSA-N
InChI1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)
mode of actionenzyme | inhibits, DNA synthesis | interferes
Quality Level200
solubility1 M NaOH: soluble 50 mg/mL
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
O8757-1G
Unit:1G
List Price: $40.60
Source:List Price
ADD
Cas Number82419-36-1
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