Not available outside of the UK & Ireland.

Application

Folic acid has been used:to induce acute kidney injury in miceas a supplement to cultivate MCF-7 breast cancer cells.to construct folate or TNF-related apoptosis-including ligand (TRAIL)-conjugated nanomicelles

Biochem/physiol Actions

Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘;one carbon’; transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).

Enzyme cofactor essential for the synthesis, methylation, and repair of DNA. Folic acid supplements may reduce colorectal cancer risk.

Packaging

1, 10, 25, 100 g in glass bottle