Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl), >=96% (HPLC)

Code: c9357-1mg D2-231

Not available outside of the UK & Ireland.

Amino Acid Sequence

Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl

Biochem/physiol Actions

Antagonist of RGD peptidomimetic αVβ3 integrin contain...


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Not available outside of the UK & Ireland.

Amino Acid Sequence

Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl

Biochem/physiol Actions

Antagonist of RGD peptidomimetic αVβ3 integrin containing both anionic and cationic binding sites that straddle the RGD binding domain.

Cyclo(Ala-Arg-Gly-Asp-3-Aminomethylbenzoyl) (XJ735) is an RGD containing cyclic peptide (peptidomimetic) used as an antagonist specific to integrin Avβ3. XJ735 is used to study the role of integrin Avβ3 in cell-matrix interactions and processes.

assay≥96% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... NPY(4852)
InChI keyHRASXYOWQQTBAQ-RCBQFDQVSA-N
InChI1S/C23H32N8O7/c1-12-19(35)31-15(6-3-7-26-23(24)25)21(37)28-11-17(32)30-16(9-18(33)34)22(38)27-10-13-4-2-5-14(8-13)20(36)29-12/h2,4-5,8,12,15-16H,3,6-7,9-11H2,1H3,(H,27,38)(H,28,37)(H,29,36)(H,30,32)(H,31,35)(H,33,34)(H4,24,25,26)/t12-,15-,16-/m0/s1
Quality Level200
SMILES stringC[C@@H]1NC(=O)c2cccc(CNC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O)c2
storage temp.−20°C
technique(s)western blot: suitable, enzyme immunoassay: suitable
UniProt accession no.P01303
Cas Number153381-95-4
This product has met the following criteria: