Not available outside of the UK & Ireland.

Application

Cholesteryl hemisuccinate tris salt has been used:to prepare solubilization buffer for glucan synthase assayto prepare immunoprecipitation buffer for immobilization of opioid receptors on paramagnetic beads.as a membrane stabilizer for liposomes and protein synaptogyrin-1 as a component of a folate-modified self-microemulsifying drug delivery system. with N-dodecyl β-D-maltoside (DDM) to solubilize erythrocyte ghosts and chemokine receptor CCR1for protein solubilization

Biochem/physiol Actions

Cholesteryl hemisuccinate is an ionizable anionic detergent that stabilizes large unilamellar vesicles. These liposome vesicles act as delivery agents for anticancer drugs, oligonucleotides and antibiotics. Cholesteryl succinate also reportedly exhibits antiproliferative activity and may be clinically useful as antitumor agent.

Packaging

5, 25 g in poly bottle

Preparation Note

Cholesteryl hemisuccinate tris salt yields clear, colorless solution in methanol at 10 mg/ml.