Tris(2-carboxyethyl)phosphine hydrochloride, BioUltra, >=98% (NMR)

Code: 75259-1g D2-231

Not available outside of the UK & Ireland.

Application

Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.

Tris(2-carboxyethyl)ph...


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£133.00 1G
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Not available outside of the UK & Ireland.

Application

Water soluble reagent, used for selective reduction of disulfides. More stable than DTT and useful in mass spectrometry applications.

Tris(2-carboxyethyl)phosphine hydrochloride has been used:as a component of IRE1 dialysis buffer, RNA cleavage buffer, and in in vitrocleavage assay ofin vitrotranscribed RNA in reducing sulfhydryl groups to obtain total thiol fractionto reduce protein samples

General description

Tris(2-carboxyethyl)-phosphine hydrochloride (TCEP) is a strong reducing agent that is stable in an aqueous solution. It readily and stoichiometrically reduces disulfides with high specificity. TCEP exhibits reducing activity at pH 1.5 to pH 9.0 and reduces dehydroascorbic acid (DHA) at pH 4.

λ0.1 M in H2O
anion tracessulfate (SO42-): ≤50 mg/kg
assay≥98% (NMR)
cation tracesBi: ≤5 mg/kg, Na: ≤50 mg/kg, Mo: ≤5 mg/kg, Al: ≤5 mg/kg, As: ≤0.05 mg/kg, K: ≤50 mg/kg, Li: ≤5 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Sr: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, Fe: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
formcrystals
InChI keyPBVAJRFEEOIAGW-UHFFFAOYSA-N
InChI1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H
loss≤1.0% loss on drying
pH1.2-1.5
product lineBioUltra
Quality Level200
SMILES stringCl[H].OC(=O)CCP(CCC(O)=O)CCC(O)=O
solubilityH2O: 1 M, clear, colorless (no residue)
storage temp.2-8°C
UV absorptionλ: 260 nm Amax: 0.05, λ: 280 nm Amax: 0.03
Code
Description
Unit Size
List Price
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75259-10G
Tris(2-carboxyethyl)phosphine hydrochloride, BioUltra, >=98% (NMR)

Unit:10G
List Price: £689.00
Source:List Price
ADD
Cas Number51805-45-9
Hazard Class8
Un Number3261
Pack GroupII
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