Not available outside of the UK & Ireland.

Application

Noursethricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.

Biochem/physiol Actions

Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.

Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.

General description

Chemical structure: peptidyl nucleoside

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

Packaging

10mg, 100mg