Proteose Peptone is an animal-based ingredient used in preparing microbiological culture media and in producing bacterial toxins. It may be used in culture medium for a variety of applications, including production of substances from the culture of bacteria, fungi, and mammalian cells. It has been reported that Proteose Peptone as supplementation to defined medium resulted in significant increases in cell number and specific monoclonal antibody production in batch culture systems.
Many factors account for the suitability of Bacto™ Proteose Peptone for the culture of fastidious pathogens, including the nitrogen components, buffering range, and the high content of proteoses. These elements create an environment beneficial to the maintenance of virulence and the elaboration of bacterial by-products. Thus, stock cultures are well preserved on media containing Bacto™ Proteose Peptone.
All animal tissues used are sourced in a controlled and validated way as to reduce risk of contamination or exposure to any diseases, especially Bovine Spongiform Encephalopathy (BSE).
Used in producing bacterial toxins, including: diphtheria toxin fom Corynebacterium diphtheria and toxins from Clostridium botulinum, Clostridium perfringens, hemolytic streptococci, pneumococcus, Salmonella pullorum (Salmonella cholerasuis subsp. cholerasuis).
This product has met the following criteria: