Fialuridine, > = 98% (HPLC)

Code: sml0632-25mg D2-231

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Fialuridine has been used in the selection of clones.

Biochem/physiol Actions

Fialuridine (1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)-...


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$716.18 25MG
DEMANDER

Non disponible en dehors du Royaume-Uni et de l'Irlande

Application

Fialuridine has been used in the selection of clones.

Biochem/physiol Actions

Fialuridine (1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)-5-iodouracil, or FIAU) and its metabolites blocks DNA polymerase at sites of multiple adjacent analog incorporation, reduces the presence of mtDNA (mitochondrial DNA) and results in mitochondrial structural defects in cultured hepatoblasts. It is considered as an efficient drug against hepatitis B virus (HBV) infection.

Fialuridine is a nucleoside analog antiviral agent. The compound displays significant mitochondrial toxicity.

General description

Fialuridine (1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)-5-iodouracil, or FIAU) is an antiviral agent. It is a thymidine-based nucleoside analogue.

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyIPVFGAYTKQKGBM-BYPJNBLXSA-N
InChI1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m1/s1
Quality Level100
SMILES stringF[C@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(NC(C(I)=C2)=O)=O
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.−20°C
Cas Number69123-98-4
Ce produit répond aux critères suivants pour être admissible aux récompenses suivantes :



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