Not available outside of the UK & Ireland.
Application
4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist:to study its effects on Madin-Darby canine kidney (MDCK) cellsto study its effects on Ca2+ influx in mice fallopian tubal cellsto study its effects on hind paw swelling in mice
Biochem/physiol Actions
4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.
Caution
Photosensitive
Packaging
1, 5 mg in ampule
Reconstitution
Stock solution cannot be made in aqueous media; dissolve in a water-miscible organic solvent before dilution to working concentrations in aqueous media.
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