Not available outside of the UK & Ireland.

Application

DNA intercalator. Also used to increase transfection efficiency.Chloroquine diphosphate salt has been used :in in vitro antiplasmodial assays in transfection and infection assaysin autophagy inhibitionin differentiation of induced pluripotent stem (iPS) cells into cardiomyocytesin flow treatment of infected blood

Biochem/physiol Actions

Standard anti-malarial drug. Substrate for MRP in multidrug resistant cell line and inhibits photoaffinity labeling of MRP by quinoline-based photoactive drug IAAQ (N-[4-[1-hydroxy-2-(dibutylamino)ethyl]quinolin-8-yl]-4-azidosalicylamide).

Features and Benefits

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General description

Chloroquine is a member of quinolone family and is a weak intercalating agent. Chloroquine is used for treating amebiasis, rheumatoid arthritis, discoid and systemic lupus erythematosus.

Packaging

25, 50, 100, 250 g in glass bottle