Not available outside of the UK & Ireland.

Application

8-Bromoadenosine 3′,5′-cyclic monophosphate sodium salt has been used:to study its effect on fas and caspase-3 mRNA expression and on P4 production in bovine mid luteal cell cultureused to treat choriocarcinoma BeWo cell line and study its effect on cell viability, apoptosis and morphological changes in the nucleiin superfusion medium for head kidneys stimulation

Biochem/physiol Actions

Cell-permeable cAMP analog having greater resistance to hydrolysis by phosphodiesterases than cAMP. Activates protein kinase A, inhibits growth, decreases proliferation, increases differentiation, and induces apoptosis of cultured cells.

Caution

Sensitive to light and moisture.

Features and Benefits

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General description

8-Bromoadenosine 3′:5′-cyclic monophosphate is a brominated cyclic mononucleotide.

Other Notes

Membrane-permeable cAMP analog.

Packaging

5, 25 mg in glass bottle

100, 250 mg in poly bottle