1(S),9-(-)-Bicuculline methbromide, >=98% (HPLC), solid

Code: b7561-125mg D2-231

Not available outside of the UK & Ireland.

Application

1(S),9(R)-(-)-Bicuculline methbromide has been used:as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culturein artific...


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Not available outside of the UK & Ireland.

Application

1(S),9(R)-(-)-Bicuculline methbromide has been used:as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culturein artificial cerebrospinal fluid (ACSF) formature dentate granule neuronsin hypothalamic explant cultures

Biochem/physiol Actions

1(S),9(R)-(−)-Bicuculline methbromide is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels. It is the water-soluble derivative of (+)-bicuculline.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

25, 125 mg in glass bottle

assay≥98% (HPLC)
colorwhite to off-white
formsolid
InChI keyBWXCECYGGMGBHD-GRTNUQQKSA-M
InChI1S/C21H20NO6.BrH/c1-22(2)6-5-11-7-15-16(26-9-25-15)8-13(11)18(22)19-12-3-4-14-20(27-10-24-14)17(12)21(23)28-19;/h3-4,7-8,18-19H,5-6,9-10H2,1-2H3;1H/q+1;/p-1/t18-,19+;/m0./s1
Quality Level100
SMILES string[Br-].C[N+]1(C)CCc2cc3OCOc3cc2[C@H]1[C@@H]4OC(=O)c5c6OCOc6ccc45
solubilityH2O: >10 mg/mL
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
B7561-25MG
1(S),9-(-)-Bicuculline methbromide, >=98% (HPLC), solid

Unit:25MG
List Price: $201.00
Source:List Price
ADD
Cas Number66016-70-4
Hazard Class6.1
Un Number1544
Pack Group3
This product has met the following criteria: