Quinine hemisulfate salt monohydrate, synthetic, >=90% (HPLC)

Code: q1250-5g D2-231

Not available outside of the UK & Ireland.

Application

Quinine hemisulfate salt monohydrate has been used as a stimuli to evaluate its influence on sensory and cognitive factors.

Biochem/physiol Actions<...


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$34.87 5G
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Not available outside of the UK & Ireland.

Application

Quinine hemisulfate salt monohydrate has been used as a stimuli to evaluate its influence on sensory and cognitive factors.

Biochem/physiol Actions

Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Quinine has analgesic property.

Features and Benefits

This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

5, 10, 50 g in glass bottle

antibiotic activity spectrumparasites
assay≥90% (HPLC)
biological sourcesynthetic
InChI keyZHNFLHYOFXQIOW-LPYZJUEESA-N
InChI1S/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19-,20+;;;/m00.../s1
mode of actionenzyme | inhibits
mp~225 °C (dec.) (lit.)
originatorBayer
Quality Level200
SMILES stringO.O.OS(O)(=O)=O.COc1ccc2nccc([C@@H](O)C3CC4CCN3C[C@@H]4C=C)c2c1.COc5ccc6nccc([C@@H](O)C7CC8CCN7C[C@@H]8C=C)c6c5
solubilityethanol: 8 mg/mL, H2O: slightly soluble 1.2 mg/mL
Cas Number207671-44-1
This product has met the following criteria to qualify for the following awards:



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