Pinacidil monohydrate, powder

Code: p154-100mg D2-231

Not available outside of the UK & Ireland.

Application

Pinacidil monohydrate has been used:in repolarization studies by infusing into left anterior descending artery (LAD)to induce ATP-sensitive K+ (KA...


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Your Price
$169.03 100MG

Not available outside of the UK & Ireland.

Application

Pinacidil monohydrate has been used:in repolarization studies by infusing into left anterior descending artery (LAD)to induce ATP-sensitive K+ (KATP) current in ventricular myocytes for electrophysiological studiesas a KATP opener to treat myocardial cells

Biochem/physiol Actions

Pinacidil is a KATP channel agonist. It protects cardiomyocytes by preventing loss of mitochondrial membrane potential. It prevents the caspase 3 activation in hypoxia/reoxygenation injury.

K+ channel activator; antihypertensive.

Packaging

100, 500 mg in poly bottle

1 g in poly bottle

colorwhite to beige
formpowder
Gene Informationhuman ... ABCC9(10060), KCNJ11(3767)mouse ... Kcnj11(16514)rat ... Kcna1(24520), Kcnj1(24521), Kcnj11(83535), Kcnj5(29713), Kcnj8(25472)
InChI keyAFJCNBBHEVLGCZ-UHFFFAOYSA-N
InChI1S/C13H19N5.H2O/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11;/h5-8,10H,1-4H3,(H2,15,16,17,18);1H2
Quality Level200
SMILES stringO.CC(NC(Nc1ccncc1)=NC#N)C(C)(C)C
solubilityDMSO: 15 mg/mL, clear, 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 40 mg/mL
Code
Description
Unit Size
List Price
Qty
P154-1G
Unit:1G
List Price: $1,003.50
Source:List Price
ADD
P154-500MG
Unit:500MG
List Price: $671.54
Source:List Price
ADD
Cas Number85371-64-8
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