5-Pregnen-3beta-ol-20-one-16alpha-carbonitrile, >=97%

Code: p0543-250mg D2-231

Not available outside of the UK & Ireland.

Application

5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:in the induction of cytochrome P450as pregnane X receptor (PXR) activator in human liver cell lines.

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$450.73 250MG

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OVERVIEW

Not available outside of the UK & Ireland.

Application

5-Pregnen-3β-ol-20-one-16α-carbonitrile has been used:in the induction of cytochrome P450as pregnane X receptor (PXR) activator in human liver cell lines.

Biochem/physiol Actions

Pregnenolone-16a-carbonitrile (PCN) is a glucocorticoid receptor antagonist and a PXR (pregnane X receptor) activator.

Packaging

50 mg in glass insert

100, 250 mg in poly bottle

SPECIFICATIONS

assay	≥97%
biological source	synthetic (organic)
form	powder, crystals or chunks
InChI key	VSBHRRMYCDQLJF-ZDNYCOCVSA-N
InChI	1S/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1
Quality Level	100
shipped in	ambient
SMILES string	C[C@@]12[C@](C[C@@H](C#N)[C@@H]2C(C)=O)([H])[C@]3([H])CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC1
solubility	chloroform: methanol (1:1): 50 mg/mL, clear, colorless to faintly yellow (with heat)
sterility	non-sterile
storage temp.	2-8°C
technique(s)	cell culture \| mammalian: suitable