Not available outside of the UK & Ireland.
Application
1-Naphthylacetyl spermine trihydrochloride has been used for the inhibition of calcium-permeable AMPAR (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor). It has also been used to study the involvement of AMPAR in biphasic activation of stress-activated protein kinase/extracellular signal-regulated kinase-1.
Biochem/physiol Actions
Blocks Ca2+ permeable AMPA receptor channels.
Other Notes
Synthetic analog of Joro spider toxin.
Packaging
5, 25 mg in glass bottle
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