Cimetidine,

Code: c4522-10g D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

H2 histamine receptor antagonist; I1 imidazoline receptor agonist; anti-ulcer agent. Blocks cancer metastasis by inhibiting the ...


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$178.16 10G
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

H2 histamine receptor antagonist; I1 imidazoline receptor agonist; anti-ulcer agent. Blocks cancer metastasis by inhibiting the expression of E-selectin on the surface of endothelial cells, thus blocking tumor cell adhesion.

Features and Benefits

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

formpowder
Gene Informationhuman ... ABCB1(5243), CYP1A2(1544), CYP3A4(1576), HRH2(3274), SLC9A2(6549), SLC9A5(6553)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Slc9a1(24782), Slc9a3(24784), Slc9a5(192215)
InChI keyAQIXAKUUQRKLND-UHFFFAOYSA-N
InChI1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
originatorGlaxoSmithKline
Quality Level200
SMILES stringCNC(NC#N)=NCCSCc1nc[nH]c1C
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
C4522-5G
Cimetidine,

Unit:5G
List Price: $97.01
Source:List Price
ADD
C4522-25G
Cimetidine,

Unit:25G
List Price: $417.24
Source:List Price
ADD
Cas Number51481-61-9
This product has met the following criteria: