Cyclophosphamide monohydrate, (HPLC), bulk package

Code: c0768-25g D2-231

Not available outside of the UK & Ireland.

Application

Cyclophosphamide monohydrate has been used:to test its antitumor effect on TC-1 tumor cellsas a component of multidrug solution for isolation of resistant human b...


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Your Price
$804.01 25G

Not available outside of the UK & Ireland.

Application

Cyclophosphamide monohydrate has been used:to test its antitumor effect on TC-1 tumor cellsas a component of multidrug solution for isolation of resistant human burkitt lymphoma cell linein testing antitumor immunity in mouse tumor cell lines

Biochem/physiol Actions

Cyclophosphamide is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

General description

Cyclophosphamide (CYC) is a cytotoxic alkylating agent. It is activated by the cytochrome P-450 enzyme system in the liver. It has immunomodulatory functionality and inhibits humoral and cellular immunity.

Packaging

1, 5, 10, 25 g in glass bottle

assay97.0-103.0% (HPLC)
formpowder
Gene Informationhuman ... ALDH1A1(216), ALDH1B1(219)
InChI keyPWOQRKCAHTVFLB-UHFFFAOYSA-N
InChI1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2
mp49-51 °C (lit.)
Quality Level200
SMILES string[H]O[H].ClCCN(CCCl)P1(=O)NCCCO1
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
C0768-10G
Unit:10G
List Price: $394.40
Source:List Price
ADD
C0768-1G
Unit:1G
List Price: $61.67
Source:List Price
ADD
C0768-5G
Unit:5G
List Price: $231.46
Source:List Price
ADD
Cas Number6055-19-2
Hazard Class6.1
Un Number3464
Pack Group3
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