III-31-C, >=98% (HPLC), solid

Code: c0619-5mg D2-231

Not available outside of the UK & Ireland.

Biochem/physiol Actions

III-31-C is a (hydroxyethyl)urea γ-secretase inhibitor that binds to γ-secretase at the substrate docking site. DAPT, also a γ-secretas...


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£370.00 5MG
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Not available outside of the UK & Ireland.

Biochem/physiol Actions

III-31-C is a (hydroxyethyl)urea γ-secretase inhibitor that binds to γ-secretase at the substrate docking site. DAPT, also a γ-secretase inhibitor binds to the substrate docking site as well. III-31-C is useful for the affinity isolation and characterization of the protease complex and for testing other ihhibitors that affect the γ-secretase active site. The γ-secretase complex is composed of presenilin as a catalytic component and three integral membrane proteins, nicastrin, Aph-1 and Pen-2.

Packaging

1, 5 mg in glass bottle

assay≥98% (HPLC)
formsolid
InChI keyDINAVFJXFRFCRE-BLFWRVEASA-N
InChI1S/C35H52N4O7/c1-23(2)19-28(31(41)38-30(24(3)4)32(42)45-8)36-33(43)39(21-26-17-13-10-14-18-26)22-29(40)27(20-25-15-11-9-12-16-25)37-34(44)46-35(5,6)7/h9-18,23-24,27-30,40H,19-22H2,1-8H3,(H,36,43)(H,37,44)(H,38,41)/t27-,28-,29+,30?/m0/s1
Quality Level100
SMILES stringCOC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)N(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C)Cc2ccccc2)C(C)C
solubilityDMSO: ≥9 mg/mL
storage conditiondesiccated
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
C0619-1MG
III-31-C, >=98% (HPLC), solid

Unit:1MG
List Price: £99.30
Source:List Price
ADD
Cas Number398515-96-3
This product has met the following criteria: