Bisindolylmaleimide ii

Code: b3056-1mg D2-231

Not available outside of the UK & Ireland.

Application

Bisindolylmaleimide II (BIS II) has been used:as a protein kinase C (PKC) inhibitor to study its effects on cardiomyocyte phenotypesas a PKC inhibitor along with ...


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$159.89 1MG
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Not available outside of the UK & Ireland.

Application

Bisindolylmaleimide II (BIS II) has been used:as a protein kinase C (PKC) inhibitor to study its effects on cardiomyocyte phenotypesas a PKC inhibitor along with methanandamide (mAEA) to study its effects on murine gastric vagal afferent(GVA) mechanosensitivityas a PKC/protein kinase A (PKA) inhibitor to study its effects on bone-marrow cells

Biochem/physiol Actions

Bisindolylmaleimide II (BIS II) acts as a dual protein kinase A/C (PKA/C) inhibitor.

assay≥97% (Mixture of 2 isomers)
biological sourcesynthetic (organic)
formpowder
InChI keyLBFDERUQORUFIN-UHFFFAOYSA-N
InChI1S/C27H26N4O2/c1-30-13-6-7-17(30)12-14-31-16-21(19-9-3-5-11-23(19)31)25-24(26(32)29-27(25)33)20-15-28-22-10-4-2-8-18(20)22/h2-5,8-11,15-17,28H,6-7,12-14H2,1H3,(H,29,32,33)
Quality Level200
shipped indry ice
SMILES stringCN1CCCC1CCn2cc(C3=C(C(=O)NC3=O)c4c[nH]c5ccccc45)c6ccccc26
solubilityethanol: soluble, DMSO: soluble
storage temp.−20°C
This product has met the following criteria: