Boc-Asp(OMe)-fluoromethyl ketone, >=90% (TLC), solid

Code: b2682-3mg D2-231

Not available outside of the UK & Ireland.

Application

Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus...


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Your Price
£883.00 3MG
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Not available outside of the UK & Ireland.

Application

Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) has been used as a caspase inhibitor to study its effects on lactate dehydrogenase (LDH) leakage, apoptosis and virus proliferation in chorion cells , as a component of the transplantation medium for the transplantation of human embryonic stem cells (ESC)-derived medial ganglionic eminence (MGE) cells into hippocampus of mice , as a protease inhibitor to study its effects on cell death in parasites .

Biochem/physiol Actions

Boc-Asp(OMe)-fluoromethyl ketone (Boc-D-fmk) permits cell permeability. It is a caspase inhibitor and suppresses apoptosis induced by various kinds of stimuli. Boc-D-fmk poorly inhibits caspases-2, -5, -6 and -10.

Packaging

3 mg in glass bottle

assay≥90% (TLC)
formsolid
InChI keyMXOOUCRHWJYCAL-ZETCQYMHSA-N
InChI1S/C11H18FNO5/c1-11(2,3)18-10(16)13-7(8(14)6-12)5-9(15)17-4/h7H,5-6H2,1-4H3,(H,13,16)/t7-/m0/s1
Quality Level100
SMILES stringCOC(=O)C[C@H](NC(=O)OC(C)(C)C)C(=O)CF
solubilityDMF: soluble
storage temp.−20°C
Cas Number187389-53-3
This product has met the following criteria: