Adenosine 3,5-cyclic monophosphate, >=98.5% (HPLC), powder

Code: a9501-1g D2-231

Not available outside of the UK & Ireland.

Application

Adenosine 3′,5′-cyclic monophosphate has been used:as cell culture medium supplement in embryonic spinal neuronsas a component of ringer solution for perfusion st...


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$299.98 1G
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Not available outside of the UK & Ireland.

Application

Adenosine 3′,5′-cyclic monophosphate has been used:as cell culture medium supplement in embryonic spinal neuronsas a component of ringer solution for perfusion studiesto induce neuroendocrine differentiation in human lung cancer cell lines

Biochem/physiol Actions

Naturally-occurring activator of cyclic-AMP-dependent protein kinase (PKA). cAMP is an important second messenger that is linked in many systems to neurotransmitter- or hormone-induced receptor stimulation. The cAMP/PKA signaling pathway has been shown to inhibit cell proliferation, induce differentiation and lead to apoptosis.

Features and Benefits

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

1, 5, 25 g in poly bottle

assay≥98.5% (HPLC)
colorwhite
formpowder
Gene Informationhuman ... OPRK1(4986)
InChI keyIVOMOUWHDPKRLL-KQYNXXCUSA-N
InChI1S/C10H12N5O6P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(16)7-4(20-10)1-19-22(17,18)21-7/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
mp260 °C (dec.) (lit.)
Quality Level200
SMILES stringNc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O
solubilityH2O: 10 mg/mL, clear, colorless (pH of aqueous solution is approx. 3.0. The sodium salt (A6885) is about 20× more soluble.)
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
A9501-25G
Adenosine 3,5-cyclic monophosphate, >=98.5% (HPLC), powder

Unit:25G
List Price: $4,294.16
Source:List Price
ADD
A9501-5G
Adenosine 3,5-cyclic monophosphate, >=98.5% (HPLC), powder

Unit:5G
List Price: $1,148.15
Source:List Price
ADD
Cas Number60-92-4
This product has met the following criteria: