A-317491 sodium salt hydrate, >=98% (HPLC), powder

Code: a2979-5mg D2-231

Not available outside of the UK & Ireland.

Application

A-317491 sodium salt hydrate has been used to block the P2X3 receptor. It has also been used to block the increased membrane conductance.

Biochem/ph...


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Your Price
$226.90 5MG
REQUEST

Not available outside of the UK & Ireland.

Application

A-317491 sodium salt hydrate has been used to block the P2X3 receptor. It has also been used to block the increased membrane conductance.

Biochem/physiol Actions

A-317491 helps to decrease neuropathic and inflammatory pain by inhibiting the P2X3 receptor-mediated Ca2+ influx.

Novel P2X3 and P2X2/3 receptor antagonist

Features and Benefits

This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

Subject to U.S. Patent No. 6,831,193. Sold under license from Abbott Laboratories

Packaging

5, 25 mg in glass bottle

assay≥98% (HPLC)
colorwhite to beige
formpowder
InChI keyVEMCGHRDAPMXLI-VYEUTZPBSA-N
InChI1S/C33H27NO8.Na.H2O.H/c35-30(25-17-27(32(38)39)28(33(40)41)18-26(25)31(36)37)34(29-15-7-10-21-9-4-5-14-24(21)29)19-20-8-6-13-23(16-20)42-22-11-2-1-3-12-22;;;/h1-6,8-9,11-14,16-18,29H,7,10,15,19H2,(H,36,37)(H,38,39)(H,40,41);;1H2;/t29-;;;/m0.../s1
originatorAbbott
Quality Level100
SMILES string[Na].[H]O[H].OC(=O)c1cc(C(O)=O)c(cc1C(O)=O)C(=O)N(Cc2cccc(Oc3ccccc3)c2)[C@H]4CCCc5ccccc45
solubilityH2O: 15 mg/mL, clear
Cas Number475205-49-3
This product has met the following criteria to qualify for the following awards:



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