Not available outside of the UK & Ireland.

Application

Anti-CHOP, N-Terminal antibody has been used in protein extraction and western blotting.

Biochem/physiol Actions

CCAAT/enhancer-binding protein homologous protein (CHOP) controls endoplasmic reticulum (ER) stress-mediated apoptosis. It also modulates the transcription of cellular lipid metabolism. CHOP controls chronic kidney disease–induced vascular calcification.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Features and Benefits

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General description

Anti-CHOP Antibody detects endogenous levels of total CHOP protein.

CCAAT/enhancer-binding protein homologous protein (CHOP) is a transcriptional regulator, that is located on human chromosome 12q13. It is also known as DNA damage inducible transcript 3 (DDIT3).

Immunogen

The antiserum was produced against synthesized peptide derived from human CHOP.Immunogen Range: 15-64

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.