Not available outside of the UK & Ireland.

Analysis Note

ControlTested on adult rat brain lysate

Application

Anti-Aquaporin 4 Antibody is an antibody against Aquaporin 4 for use in WB.

Western Blotting: 0.5-1 µg/mL using Chemiluminescence technique.

Optimal working dilutions must be determined by end user.

Research Sub CategoryIon Channels & Transporters

Research CategoryNeuroscience

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The water-specific channel Aquaporin 4 is located in various tissues including the gastro intestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. The localization of AQ4 to astrocyte endfeet makes it an excellent marker for astrocyte distal processes.

Immunogen

Epitope: C-Terminus

Synthetic Linear Peptide

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Linkage

Replaces: AB3068

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

ImmunoAffinity Purified

Purified in PBS with 0.05% NaN₃

Specificity

Recognizes Aquaporin 4.

The antibody has not yet been tested for cross-reactivity to other species. The immunogen shows 94% similarity to mouse, 88% to bovine, 86% to rabbit and 82% to human AQP4 (hAQP4).

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Target description

~34 kDa