Not available outside of the UK & Ireland.

General description

Native prothrombin from human plasma. Vitamin K-dependent glycoprotein synthesized in the liver. Conversion to thrombin is a key step in the blood coagulation pathway and catalyzes the coagulation of fibrinogen. Clinically, cases of selective deficiency are rare, although, in cases of liver cirrhosis, prothrombin is decreased.

Native prothrombin from human plasma. Vitamin K-dependent glycoprotein synthesized in the liver. Conversion to thrombin is a key step in the blood coagulation pathway and catalyzes the coagulation of fibrinogen. Clinically, cases of selective deficiency are rare, although in cases of liver cirrhosis, prothrombin is decreased.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Packaging

1, 2 mg in Plastic ampoule

Physical form

Lyophilized from 100 mM NaCl, 20 mM Tris-HCl, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Please refer to the label for lot-specific reconstitution volume.

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C.r>

Warning

Toxicity: Standard Handling (A)