Not available outside of the UK & Ireland.

Biochem/physiol Actions

ED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.

General description

Recombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses.

Recombinant, human γ-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses. Expressed in and purified from E. coli.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kohji, K., et al. 1994. J. Int. J. Cancer 58, 380.Kolb, J.P., et al. 1994. J. Biol. Chem.269, 9811.Müller, U., et al. 1994. Science264, 1918.Zahedi, K., et al. 1994. J. Biol. Chem.269, 9669.Shuai, K., et al. 1993. Science261, 1744.Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA89, 11964.Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.

Packaging

100 µg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Physical form

Sterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C). Do not store in glass vials without addition of carrier protein. Further dilute in low endotoxin medium or buffer containing FBS or tissue culture grade BSA.

Warning

Toxicity: Standard Handling (A)